Volume 1 of The Apothecary Diaries was a proof of concept. Here’s Maomao. She’s brilliant, she’s caustic, she solves mysteries with medicine. You’re in or you’re out. Volume 2 is where Natsu Hyuuga starts proving this isn’t a one-trick series. The mysteries get more personal. The politics get nastier. And a character walks into the story who changes everything about how Maomao operates in the palace.
I finished Volume 1 thinking I had a solid mystery-of-the-week light novel on my hands. I finished Volume 2 realizing I had something with actual teeth.

What Happens in Volume 2
The big set piece is the imperial garden party. Consorts, officials, enough political tension to poison a banquet (which, nearly, someone does). Maomao gets pulled into preparations and ends up investigating food that’s been deliberately tampered with. Not with anything exotic. Just honey, given to the wrong person at the wrong time.
The target is Consort Lishu, the youngest and most vulnerable of the Emperor’s consorts. Her ladies-in-waiting have been systematically mistreating her, and the honey incident is the culmination of something uglier than a single poisoning attempt. Lishu has a severe reaction. Not from poison in the traditional sense, but from food her own attendants should have known she couldn’t eat. Whether it’s incompetence or malice is the question, and Maomao approaches it with her usual clinical detachment. But the answer she finds makes it hard to stay detached.
Beyond the garden party, Volume 2 introduces Lakan. He’s a military strategist who shows up at court playing shogi against anyone foolish enough to sit down opposite him. He wins every game. Unsettlingly perceptive. And he knows who Maomao is. Not just the version of her that works in the Jade Pavilion. The other version. The one tied to the pleasure district and a past she hasn’t fully shared with anyone at court.
There’s also a fire at one of the Rear Palace storehouses that Maomao investigates, which functions as a smaller mystery, but ties back into the larger web of sabotage running through the volume. Everything in Volume 2 connects more tightly than Volume 1’s episodic structure. The cases aren’t standalone puzzles anymore.
Maomao Under Pressure
What makes Volume 2 land harder is that Maomao can’t fully control the situation. In Volume 1, she solved problems from a safe distance. The clever apothecary who figures things out while everyone else fumbles around. Here, she’s directly in the crosshairs. Lakan’s presence means someone at court knows her background. The garden party puts her physically in danger. Jinshi can’t always intervene.
The best scenes in the volume are the ones where Maomao’s carefully maintained detachment starts showing cracks. She still narrates everything through her pharmacist’s lens, still catalogs poisons and symptoms the way other people notice weather. But when the investigation points toward Lishu’s ladies-in-waiting — women who were supposed to protect a teenage girl and instead let her suffer — you can feel the anger underneath the analysis. Maomao doesn’t monologue about it. She just acts faster.
That restraint is what separates this from lesser light novels. A weaker writer would have Maomao deliver a speech about injustice. Hyuuga lets the reader connect the dots from her behavior. It’s genuinely good character writing.
Lakan Changes the Series
I want to talk about Lakan more because he fundamentally shifts what kind of story this is. Volume 1’s antagonists were situations: poisoned makeup, contaminated food, palace superstition. Volume 2 introduces an actual person who can match Maomao’s intelligence and has reasons to make her life complicated.
He’s not a villain in any straightforward sense. He’s a strategist who treats human relationships like board games, which makes him both fascinating and deeply unsettling. His connection to Maomao’s origins in the pleasure district gets teased more than explained in this volume, but even the hints reframe everything you thought you understood about why she ended up at court.
If you’ve watched the anime, you know where the Lakan thread goes eventually. But reading it here, in Maomao’s voice, with her carefully controlled reactions to seeing him — it hits different. The anime plays their encounters with dramatic music and meaningful glances. The novel gives you Maomao cataloging his physical appearance, noting his strategic habits, and very deliberately not thinking about certain things. The avoidance tells you more than any dramatic reveal would.
The Jinshi Dynamic, Evolved
The Maomao-Jinshi relationship also levels up. In Volume 1, their dynamic was mostly comedic. The beautiful man baffled by the woman who won’t swoon. Volume 2 adds real stakes. Jinshi puts himself in politically risky positions to protect Maomao. She notices but processes it as data rather than feeling, which is both funny and kind of heartbreaking if you’re paying attention.
There’s a scene after the garden party where Jinshi is genuinely furious about the danger Maomao was in, and she responds by analyzing his facial expressions like she’s reading a medical chart. It’s the kind of moment that works because Hyuuga has built enough trust with the reader that you understand what Maomao isn’t saying.
Who This Volume Is For
If Volume 1 convinced you that Maomao was worth following, Volume 2 justifies the commitment. The mysteries are sharper. The character work goes deeper. Lakan’s introduction raises the series from “good mystery light novel” to something with genuine narrative ambition.
Anime watchers who felt Season 1’s second half got more intense — this is where that shift starts. The light novel gives you everything the anime had plus Maomao’s full internal processing, which makes scenes like the Lishu reveal and the Lakan encounters significantly more impactful. For a detailed breakdown of adaptation differences, check our Apothecary Diaries manga vs anime comparison.
If you bounced off Volume 1 for being too episodic, give Volume 2 a shot. The structure tightens considerably. And if you read Volume 1 and loved it, you’re about to like this series a lot more.
Where to Get It
Volume 2 is available on Amazon in print from Square Enix Manga & Books (approximately 256 pages) and digitally. Kevin Steinbach’s translation continues from Volume 1 and maintains the same sharp, readable prose.
Two volumes in, and The Apothecary Diaries has already outgrown its setup. Volume 1 gave you a clever protagonist solving palace mysteries. Volume 2 gives you a story that’s actually going somewhere — and someone who might be smart enough to get in Maomao’s way.
TL;DR
- Volume 2 is where The Apothecary Diaries proves it isn’t a one-trick series. The mysteries get more personal. The politics get nastier. A character walks in who changes everything about how Maomao operates.
- I finished Volume 1 thinking I had a solid mystery-of-the-week LN. I finished Volume 2 realizing I had something with actual teeth.
- The court intrigue deepens significantly. Volume 1 established the setting. Volume 2 starts using it.
